Since the beginning of history, epidemic diseases have been one of the threatening factors, not only for the health of human beings, but also to disrupt or stop the growth and development of societies and even at times, it has caused the death of millions of people. For this reason, there is a very close connection between the right to health as one of the examples of ensuring the right to life and human security. On the other hand, one of the components of human security is health security. The meaning of providing health security is that people have security against the threats caused by diseases, disability and death as pervasive threats and do not see their health at risk of being affected by these threats. Epidemic diseases do not remain within the borders of a country or region due to the characteristic of rapid spread and the faster and easier global human communication becomes, the spread of epidemic diseases has also become easier and for this reason, as Pervasive threats are known in the world. For this purpose, both from the point of view of jurisprudential standards such as the rule of the obligation to prevent possible harm and the rule of harmlessness and from the point of view that in the Islamic system, the government is obliged to provide a platform for the perfection of man, it is to be recognized as responsible in dealing with epidemic diseases. Also, the government in the system of the Islamic Republic of Iran is responsible for the right to the health of the people according to the constitution and higher documents of the country. In the international arena, epidemic diseases are recognized as one of the main challenges of humanity. To such an extent that the United Nations Security Council has introduced the spread of AIDS and Ebola as a threat to humanity. Also, according to the international health regulations of the World Health Organization, the protection of basic human freedoms in line with the United Nations Charter, the duty of protecting all people from infectious diseases has been entrusted to the member states.